Murine Broadly Reactive Antineuraminidase Monoclonal Antibodies Protect Mice from Recent Influenza B Virus Isolates and Partially Inhibit Virus Transmission in the Guinea Pig Model

Murine Broadly Reactive Antineuraminidase Monoclonal Antibodies Protect Mice from Recent Influenza B Virus Isolates and Partially Inhibit Virus Transmission in the Guinea Pig Model

ABSTRACT Current influenza virus vaccines and antivirals have limitations, some of which disproportionately affect their utilization against influenza B viruses. To inform ongoing efforts to address the considerable global burden of influenza B viruses, we previously described five murine monoclonal...

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Bibliographic Details
Main Authors: Jessica Tan, Veronika Chromikova, George O'Dell, Emilia Mia Sordillo, Viviana Simon, Harm van Bakel, Florian Krammer, Meagan McMahon
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:mSphere
Subjects:
Influenza
experimental therapeutics
monoclonal antibodies
Online Access:https://journals.asm.org/doi/10.1128/msphere.00927-21

Internet

https://journals.asm.org/doi/10.1128/msphere.00927-21

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