Genetically engineered CD80–pMHC-harboring extracellular vesicles for antigen-specific CD4+ T-cell engagement

Genetically engineered CD80–pMHC-harboring extracellular vesicles for antigen-specific CD4+ T-cell engagement

The identification of low-frequency antigen-specific CD4+ T cells is crucial for effective immunomonitoring across various diseases. However, this task still encounters experimental challenges necessitating the implementation of enrichment procedures. While existing antigen-specific expansion techno...

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Bibliographic Details
Main Authors: Irina A. Ishina, Inna N. Kurbatskaia, Azad E. Mamedov, Elena I. Shramova, Sergey M. Deyev, Kamila S. Nurbaeva, Yury P. Rubtsov, Alexey A. Belogurov, Alexander G. Gabibov, Maria Y. Zakharova
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
CD4+ T cells
extracellular vesicles
major histocompatibility complex
costimulatory molecules
antigen-specific expansion
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1341685/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2023.1341685/full

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