Dose accumulation to assess the validity of treatment plans with reduced margins in radiotherapy of head and neck cancer

Background and purpose: Literature has reported reduced treatment toxicity in head-and-neck radiotherapy (HNRT) when reducing the planning target volume (PTV) margin from 5 to 3 mm but loco-regional control was not always preserved. This study used deformable image registration (DIR)-facilitated dos...

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Bibliographic Details
Main Authors: Nicholas J. Lowther, Steven H. Marsh, Robert J.W. Louwe
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Physics and Imaging in Radiation Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405631620300178