Inhibition of Butyrylcholinesterase and Human Monoamine Oxidase-B by the Coumarin Glycyrol and Liquiritigenin Isolated from <i>Glycyrrhiza uralensis</i>

Inhibition of Butyrylcholinesterase and Human Monoamine Oxidase-B by the Coumarin Glycyrol and Liquiritigenin Isolated from <i>Glycyrrhiza uralensis</i>

Eight compounds were isolated from the roots of <i>Glycyrrhiza uralensis</i> and tested for cholinesterase (ChE) and monoamine oxidase (MAO) inhibitory activities. The coumarin glycyrol (GC) effectively inhibited butyrylcholinesterase (BChE) and acetylcholinesterase (AChE) with IC<sub...

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Bibliographic Details
Main Authors: Geum Seok Jeong, Myung-Gyun Kang, Joon Yeop Lee, Sang Ryong Lee, Daeui Park, MyoungLae Cho, Hoon Kim
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Molecules
Subjects:
<i>Glycyrrhiza uralensis</i>
glycyrol
liquiritigenin
cholinesterases
human monoamine oxidases
kinetics
Online Access:https://www.mdpi.com/1420-3049/25/17/3896

Internet

https://www.mdpi.com/1420-3049/25/17/3896

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