Towards a new standardized method for circulating miRNAs profiling in clinical studies: Interest of the exogenous normalization to improve miRNA signature accuracy

Towards a new standardized method for circulating miRNAs profiling in clinical studies: Interest of the exogenous normalization to improve miRNA signature accuracy

Circulating miRNAs are promising biomarkers in oncology but have not yet been implemented in the clinic given the lack of concordance across studies. In order to increase the cross‐studies reliability, we attempted to reduce and to control the circulating miRNA expression variability between patient...

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Bibliographic Details
Main Authors: Nicolas Vigneron, Matthieu Meryet-Figuière, Audrey Guttin, Jean-Paul Issartel, Bernard Lambert, Mélanie Briand, Marie-Hélène Louis, Mégane Vernon, Pierre Lebailly, Yannick Lecluse, Florence Joly, Sophie Krieger, Stéphanie Lheureux, Bénédicte Clarisse, Alexandra Leconte, Pascal Gauduchon, Laurent Poulain, Christophe Denoyelle
Format: Article
Language:English
Published: Wiley 2016-08-01
Series:Molecular Oncology
Subjects:
Circulating miRNA
Serum
Plasma
Profiling
Normalization
Ovarian cancer
Online Access:https://doi.org/10.1016/j.molonc.2016.03.005

Internet

https://doi.org/10.1016/j.molonc.2016.03.005

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