Polygenic scores for longevity and cognitive performance are associated with predicted brain age in 70-year-olds from the general population.

Introduction: Genome-wide association studies (GWASs) have shown that several genes, beside the “high-effect” APOE gene, are involved in modulating the risk of dementia and longevity, and some of these genes overlap between the traits. Considering longevity, there are also associations with genes re...

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Bibliographic Details
Main Authors: Anna Zettergren, Nazib Seidu, Jenna Najar, Anna Marseglia, Caroline Dartora, Kaj Blennow, Henrik Zetterberg, Margda Waern, Silke Kern, Eric Westman, Ingmar Skoog
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Cerebral Circulation - Cognition and Behavior
Online Access:http://www.sciencedirect.com/science/article/pii/S2666245024001077