Australian Scorpion <i>Hormurus waigiensis</i> Venom Fractions Show Broad Bioactivity through Modulation of Bio-Impedance and Cytosolic Calcium

Australian Scorpion <i>Hormurus waigiensis</i> Venom Fractions Show Broad Bioactivity through Modulation of Bio-Impedance and Cytosolic Calcium

Scorpion venoms are a rich source of bioactive molecules, but characterisation of toxin peptides affecting cytosolic Ca<sup>2+</sup>, central to cell signalling and cell death, is limited. We undertook a functional screening of the venom of the Australian scorpion <i>Hormurus waigi...

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Bibliographic Details
Main Authors: David M. Housley, Jeremy L. Pinyon, Georg von Jonquieres, Chamini J. Perera, Michael Smout, Michael J. Liddell, Ernest A. Jennings, David Wilson, Gary D. Housley
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Biomolecules
Subjects:
membrane biophysics
scorpion toxins
xCELLigence Real Time Cell Analysis
GCaMP5G calcium reporter
ryanodine receptors
calcium store
Online Access:https://www.mdpi.com/2218-273X/10/4/617

Internet

https://www.mdpi.com/2218-273X/10/4/617

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