Identification of countercurrent tubule-vessel arrangements in the early development of mouse kidney based on immunohistochemistry and computer-assisted 3D visualization.

Nephron loop-vessel countercurrent arrangement in the medulla provides the structural basis for the formation of concentrated urine. To date, the morphogenesis of it and relevant water and solutes transportation has not been fully elucidated. In this study, with immunohistochemistry for aquaporins (...

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Bibliographic Details
Main Authors: Yun-Sheng Ma, Si-Qi Deng, Ping Zhang, Jesper Skovhus Thomsen, Arne Andreasen, Shi-Jie Chang, Jie Zhang, Ling Gu, Xiao-Yue Zhai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0307223