Friend or Foe: Protein Inhibitors of DNA Gyrase

DNA gyrase is essential for the successful replication of circular chromosomes, such as those found in most bacterial species, by relieving topological stressors associated with unwinding the double-stranded genetic material. This critical central role makes gyrase a valued target for antibacterial...

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Bibliographic Details
Main Authors: Shengfeng Ruan, Chih-Han Tu, Christina R. Bourne
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/13/2/84