A secretory protein neudesin regulates splenic red pulp macrophages in erythrophagocytosis and iron recycling
Abstract Neudesin, originally identified as a neurotrophic factor, has primarily been studied for its neural functions despite its widespread expression. Using 8-week-old neudesin knockout mice, we elucidated the role of neudesin in the spleen. The absence of neudesin caused mild splenomegaly, short...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-01-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-024-05802-9 |