Parameter estimation for robust HMM analysis of ChIP-chip data

<p>Abstract</p> <p>Background</p> <p>Tiling arrays are an important tool for the study of transcriptional activity, protein-DNA interactions and chromatin structure on a genome-wide scale at high resolution. Although hidden Markov models have been used successfully to a...

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Bibliographic Details
Main Authors: Humburg Peter, Bulger David, Stone Glenn
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/343