Nanofiber Alignment Regulates NIH3T3 Cell Orientation and Cytoskeletal Gene Expression on Electrospun PCL+Gelatin Nanofibers.

To examine the influence of substrate topology on the behavior of fibroblasts, tissue engineering scaffolds were electrospun from polycaprolactone (PCL) and a blend of PCL and gelatin (PCL+Gel) to produce matrices with both random and aligned nanofibrous orientations. The addition of gelatin to the...

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Detalhes bibliográficos
Principais autores: Timothy Fee, Swetha Surianarayanan, Crawford Downs, Yong Zhou, Joel Berry
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2016-01-01
coleção:PLoS ONE
Acesso em linha:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0154806&type=printable