Obesity induces resistance to central action of BMP8B through a mechanism involving the BBSome

Obesity induces resistance to central action of BMP8B through a mechanism involving the BBSome

Objective: Bone morphogenetic protein 8B (BMP8B) plays a major role in the regulation of energy homeostasis by modulating brown adipose tissue (BAT) thermogenesis and white adipose tissue (WAT) browning. Here, we investigated whether BMP8B's role in metabolism is affected by obesity and the pos...

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Bibliographic Details
Main Authors: Eva Rial-Pensado, Oscar Freire-Agulleiro, Marcos Ríos, Deng Fu Guo, Cristina Contreras, Patricia Seoane-Collazo, Sulay Tovar, Rubén Nogueiras, Carlos Diéguez, Kamal Rahmouni, Miguel López
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Molecular Metabolism
Subjects:
Obesity
Hypothalamus
AMPK
BAT
BMP8B
BBS1
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822000345

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http://www.sciencedirect.com/science/article/pii/S2212877822000345

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