IL-25 induces airway remodeling in asthma by orchestrating the phenotypic changes of epithelial cell and fibrocyte

Abstract Background Previous studies have shown that IL-25 levels are increased in patients with asthma with fixed airflow limitation (FAL). However, the mechanism by which IL-25 contributes to airway remodeling and FAL remains unclear. Here, we hypothesized that IL-25 facilitates pro-fibrotic pheno...

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Bibliographic Details
Main Authors: Xiujuan Yao, Qinglin Chen, Xiangdong Wang, Xiaofang Liu, Luo Zhang
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-023-02509-z