CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2/HO-1 axis, regulating CD8 + T cell response

CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2/HO-1 axis, regulating CD8 + T cell response

Abstract Background LILRB3, a member of the leukocyte immunoglobulin-like receptor B (LILRB) family, has immunosuppressive functions and directly regulates cancer development, which indicates that LILRB3 is an attractive target for cancer diagnosis and therapy. Novel therapeutic treatments for acute...

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Bibliographic Details
Main Authors: Qingyan Cen, Jianyu Chen, Jiaxin Guo, Mu Chen, Hao Wang, Suwan Wu, Honghao Zhang, Xiaoling Xie, Yuhua Li
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Translational Medicine
Subjects:
AML
LILRB3
microRNA-103a-2-5p
Nrf2/HO-1
CD8
Cationic liposomes
Online Access:https://doi.org/10.1186/s12967-024-05070-5

Internet

https://doi.org/10.1186/s12967-024-05070-5

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