Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells

Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells

T cells are crucial for efficient antigen-specific immune responses and thus their migration within the body, to inflamed tissues from circulating blood or to secondary lymphoid organs, plays a very critical role. T cell extravasation in inflamed tissues depends on chemotactic cues and interaction b...

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Bibliographic Details
Main Authors: Chinky Shiu Chen Liu, Tithi Mandal, Parijat Biswas, Md Asmaul Hoque, Purbita Bandopadhyay, Bishnu Prasad Sinha, Jafar Sarif, Ranit D'Rozario, Deepak Kumar Sinha, Bidisha Sinha, Dipyaman Ganguly
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-02-01
Series:eLife
Subjects:
Piezo1
human T cells
chemotaxis
cell migration
mechanosensing
focal adhesion kinase
Online Access:https://elifesciences.org/articles/91903

Internet

https://elifesciences.org/articles/91903

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