Stepwise differentiation of follicular helper T cells reveals distinct developmental and functional states

Abstract Follicular helper T (Tfh) cells are essential for the formation of high affinity antibodies after vaccination or infection. Although the signals responsible for initiating Tfh differentiation from naïve T cells have been studied, the signals controlling sequential developmental stages culmi...

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Bibliographic Details
Main Authors: Manuel A. Podestà, Cecilia B. Cavazzoni, Benjamin L. Hanson, Elsa D. Bechu, Garyfallia Ralli, Rachel L. Clement, Hengcheng Zhang, Pragya Chandrakar, Jeong-Mi Lee, Tamara Reyes-Robles, Reza Abdi, Alos Diallo, Debattama R. Sen, Peter T. Sage
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43427-4