In-Depth Characterization of Stromal Cells within the Tumor Microenvironment Yields Novel Therapeutic Targets

In-Depth Characterization of Stromal Cells within the Tumor Microenvironment Yields Novel Therapeutic Targets

Cells within the tumor stroma are essential for tumor progression. In particular, cancer-associated fibroblasts (CAF) and CAF precursor cells (resident fibroblasts and mesenchymal stromal cells) are responsible for the formation of the extracellular matrix in tumor tissue. Consequently, CAFs directl...

Full description

Bibliographic Details
Main Authors: Sebastian G. Walter, Sebastian Scheidt, Robert Nißler, Christopher Gaisendrees, Kourosh Zarghooni, Frank A. Schildberg
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
cancer-associated fibroblasts
mesenchymal stromal cells
fibroblast
cancer
tumor
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/13/6/1466

Internet

https://www.mdpi.com/2072-6694/13/6/1466

Similar Items