Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analyses.

Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analyses.

Genetic defects leading to the reduction of the survival motor neuron protein (SMN) are a causal factor for Spinal Muscular Atrophy (SMA). While there are a number of therapies under evaluation as potential treatments for SMA, there is a critical lack of a biomarker method for assessing efficacy of...

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Bibliographic Details
Main Authors: Dione T Kobayashi, Rory J Olson, Laurel Sly, Chad J Swanson, Brett Chung, Nikolai Naryshkin, Jana Narasimhan, Anuradha Bhattacharyya, Michael Mullenix, Karen S Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3164180?pdf=render

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http://europepmc.org/articles/PMC3164180?pdf=render

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