TMEM16F may be a new therapeutic target for Alzheimer’s disease

TMEM16F may be a new therapeutic target for Alzheimer’s disease

TMEM16F is involved in many physiological processes such as blood coagulation, cell membrane fusion and bone mineralization. Activation of TMEM16F has been studied in various central nervous system diseases. High TMEM16F level has been also found to participate in microglial phagocytosis and transfo...

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Bibliographic Details
Main Authors: Zhi-Qiang Cui, Xiao-Ying Hu, Tuo Yang, Jing-Wei Guan, Ying Gu, Hui-Yuan Li, Hui-Yu Zhang, Qing-Huan Xiao, Xiao-Hong Sun
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
alzheimer’s disease; aβ plaque; inflammatory cytokines; m1 phenotype; m2 phenotype; microglia polarization; neuroinflammation; nlrp3 inflammasome; sirna; tmem16f
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=3;spage=643;epage=651;aulast=Cui

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=3;spage=643;epage=651;aulast=Cui

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