Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development

Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development

Abstract Piezo proteins are mechanically activated ion channels, which are required for mechanosensing functions in a variety of cell types. While we and others have previously demonstrated that the expression of Piezo1 in osteoblast lineage cells is essential for bone-anabolic processes, there was...

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Bibliographic Details
Main Authors: Laura J. Brylka, Assil-Ramin Alimy, Miriam E. A. Tschaffon-Müller, Shan Jiang, Tobias Malte Ballhause, Anke Baranowsky, Simon von Kroge, Julian Delsmann, Eva Pawlus, Kian Eghbalian, Klaus Püschel, Astrid Schoppa, Melanie Haffner-Luntzer, David J. Beech, Frank Timo Beil, Michael Amling, Johannes Keller, Anita Ignatius, Timur A. Yorgan, Tim Rolvien, Thorsten Schinke
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-024-00315-x

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https://doi.org/10.1038/s41413-024-00315-x

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