Anti-Tumor Activity of <i>Hypericum perforatum</i> L. and Hyperforin through Modulation of Inflammatory Signaling, ROS Generation and Proton Dynamics

In this paper we review the mechanisms of the antitumor effects of <i>Hypericum perforatum</i> L. (St. John’s wort, SJW) and its main active component hyperforin (HPF). SJW extract is commonly employed as antidepressant due to its ability to inhibit monoamine neurotransmitters re-uptake....

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Bibliographic Details
Main Authors: Marta Menegazzi, Pellegrino Masiello, Michela Novelli
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/10/1/18