Proper Sterol Distribution Is Required for Candida albicans Hyphal Formation and Virulence

Proper Sterol Distribution Is Required for Candida albicans Hyphal Formation and Virulence

Candida albicans is an opportunistic fungus responsible for the majority of systemic fungal infections. Multiple factors contribute to C. albicans pathogenicity. C. albicans strains lacking CaArv1 are avirulent. Arv1 has a conserved Arv1 homology domain (AHD) that has a zinc-binding domain containin...

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Bibliographic Details
Main Authors: Paula McCourt, Hsing-Yin Liu, Josie E. Parker, Christina Gallo-Ebert, Melissa Donigan, Adam Bata, Caroline Giordano, Steven L. Kelly, Joseph T. Nickels Jr
Format: Article
Language:English
Published: Oxford University Press 2016-11-01
Series:G3: Genes, Genomes, Genetics
Subjects:
virulence
Candida
sterol
hyphae
lipid
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.033969

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.033969

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