Genetic inactivation of the translin/trax microRNA-degrading enzyme phenocopies the robust adiposity induced by Translin (Tsn) deletion

Objective: Deletion of Translin (Tsn) from mice induces an unusual metabolic profile characterized by robust adiposity, normal body weight and glucose tolerance. Translin (TN) protein and its partner, trax (TX), form the TN/TX microRNA-degrading enzyme. Since the microRNA system plays a prominent ro...

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Bibliographic Details
Main Authors: Xiuping Fu, Aparna P. Shah, Zhi Li, Mengni Li, Kellie L. Tamashiro, Jay M. Baraban
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820300879