Defect of IL17 Signaling, but Not Centrinone, Inhibits the Development of Psoriasis and Skin Papilloma in Mouse Models

Defect of IL17 Signaling, but Not Centrinone, Inhibits the Development of Psoriasis and Skin Papilloma in Mouse Models

Patients with psoriasis tend to develop skin cancer, and the hyperproliferation of the epidermis is a histopathological hallmark of both psoriasis and cutaneous squamous cell carcinoma (SCC), indicating that they may share pathogenic mechanisms. Interleukin-17 (IL17) stimulates the proliferation of...

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Bibliographic Details
Main Authors: Ben Jin, Yongfeng Zhang, Haiyan D. Miller, Ling He, Dongxia Ge, Alun R. Wang, Zongbing You
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomedicines
Subjects:
psoriasis
skin papilloma
IL17RA
IL17RC
centrinone
Online Access:https://www.mdpi.com/2227-9059/10/8/1976

Internet

https://www.mdpi.com/2227-9059/10/8/1976

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