TMEM100 acts as a TAK1 receptor that prevents pathological cardiac hypertrophy progression

TMEM100 acts as a TAK1 receptor that prevents pathological cardiac hypertrophy progression

Abstract Pathological cardiac hypertrophy is the primary cause of heart failure, yet its underlying mechanisms remain incompletely understood. Transmembrane protein 100 (TMEM100) plays a role in various disorders, such as nervous system disease, pain and tumorigenesis, but its function in pathologic...

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Bibliographic Details
Main Authors: Bin-Bin Zhang, Yi-Lin Zhao, Yan-Yu Lu, Ji-Hong Shen, Hui-Yong Li, Han-Xue Zhang, Xiao-Yue Yu, Wen-Cai Zhang, Gang Li, Zhan-Ying Han, Sen Guo, Xu-Tao Zhang
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Cell Communication and Signaling
Subjects:
TMEM100
TAK1
Cardiac hypertrophy
Cardiomyocyte hypertrophy
Protein–protein interaction
Online Access:https://doi.org/10.1186/s12964-024-01816-2

Internet

https://doi.org/10.1186/s12964-024-01816-2

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