Potent hemithioindigo-based antimitotics photocontrol the microtubule cytoskeleton in cellulo

Background: Hemithioindigo is a promising molecular photoswitch that has only recently been applied as a photoswitchable pharmacophore for control over bioactivity in cellulo. Uniquely, in contrast to other photoswitches that have been applied to biology, the pseudosymmetric hemithioindigo scaffold...

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Bibliographic Details
Main Authors: Alexander Sailer, Franziska Ermer, Yvonne Kraus, Rebekkah Bingham, Ferdinand H. Lutter, Julia Ahlfeld, Oliver Thorn-Seshold
Format: Article
Language:English
Published: Beilstein-Institut 2020-01-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.16.14