Integrins are mechanosensors that modulate human eosinophil activation
Eosinophil migration to the lung is primarily regulated by the eosinophil-selective family of eotaxin chemokines, which mobilize intracellular calcium (Ca2+) and orchestrate myriad changes in cell structure and function. Eosinophil function is also known to be flow-dependent, although the molecular...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2015-10-01
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Series: | Frontiers in Immunology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00525/full |