Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats

Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats

Long-term administration of l-3,4-dihydroxyphenylalanine (levodopa), the mainstay treatment for Parkinson's disease (PD), is accompanied by fluctuations in its duration of action and motor complications (dyskinesia) that dramatically affect the quality of life of patients. Levodopa-induced dysk...

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Detaylı Bibliyografya
Asıl Yazarlar: A.A. Martinez, M.G. Morgese, A. Pisanu, T. Macheda, M.A. Paquette, A. Seillier, T. Cassano, A.R. Carta, A. Giuffrida
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Elsevier 2015-02-01
Seri Bilgileri:Neurobiology of Disease
Konular:
Dyskinesia
Parkinson's disease
Cannabinoid
PPARγ
Levodopa
Rosiglitazone
Online Erişim:http://www.sciencedirect.com/science/article/pii/S0969996114003702

Internet

http://www.sciencedirect.com/science/article/pii/S0969996114003702

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