Kinins Released by Erythrocytic Stages of Plasmodium falciparum Enhance Adhesion of Infected Erythrocytes to Endothelial Cells and Increase Blood Brain Barrier Permeability via Activation of Bradykinin Receptors

Kinins Released by Erythrocytic Stages of Plasmodium falciparum Enhance Adhesion of Infected Erythrocytes to Endothelial Cells and Increase Blood Brain Barrier Permeability via Activation of Bradykinin Receptors

Background:Plasmodium falciparum, the etiologic agent of malaria, is a major cause of infant death in Africa. Although research on the contact system has been revitalized by recent discoveries in the field of thrombosis, limited efforts were done to investigate the role of its proinflammatory arm, t...

Full description

Bibliographic Details
Main Authors: Leandro S. Silva, Alessandro S. Pinheiro, Douglas E. Teixeira, Rodrigo P. Silva-Aguiar, Diogo B. Peruchetti, Julio Scharfstein, Celso Caruso-Neves, Ana Acacia S. Pinheiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Medicine
Subjects:
malaria
Plasmodium falciparum
KKS
bradykinin
endothelial barrier
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2019.00075/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2019.00075/full

Similar Items