Detection of <em>SF3B1</em> p.Lys700Glu Mutation by PNA-PCR Clamping in Myelodysplastic Syndromes and Myeloproliferative Neoplasms

Detection of <em>SF3B1</em> p.Lys700Glu Mutation by PNA-PCR Clamping in Myelodysplastic Syndromes and Myeloproliferative Neoplasms

Mutations in <i>SF3B1</i> are found in 20% of myelodysplastic syndromes and 5–10% of myeloproliferative neoplasms, where they are considered important for diagnosis and therapy decisions. Sanger sequencing and NGS are the currently available methods to identify <i>SF3B1</i> m...

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Bibliographic Details
Main Authors: Jessica Petiti, Federico Itri, Elisabetta Signorino, Antonio Frolli, Carmen Fava, Marco Armenio, Silvia Marini, Emilia Giugliano, Marco Lo Iacono, Giuseppe Saglio, Daniela Cilloni
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Journal of Clinical Medicine
Subjects:
<i>SF3B1</i> p.Lys700Glu
MDS
MPN
PNA-PCR clamping
Online Access:https://www.mdpi.com/2077-0383/11/5/1267

Internet

https://www.mdpi.com/2077-0383/11/5/1267

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