GDF15 Is an Eribulin Response Biomarker also Required for Survival of DTP Breast Cancer Cells

GDF15 Is an Eribulin Response Biomarker also Required for Survival of DTP Breast Cancer Cells

Drug tolerant persister (DTP) cells enter into a reversible slow-cycling state after drug treatment. We performed proteomic characterization of the breast cancer (BC) DTP cell secretome after eribulin treatment. We showed that the growth differentiation factor 15 (GDF15) is a protein significantly o...

Full description

Bibliographic Details
Main Authors: Chiara Bellio, Marta Emperador, Pol Castellano, Albert Gris-Oliver, Francesc Canals, Alex Sánchez-Pla, Esther Zamora, Joaquín Arribas, Cristina Saura, Violeta Serra, Josep Tabernero, Bruce A. Littlefield, Josep Villanueva
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
drug tolerance
drug tolerant persister (DTP)
eribulin
growth differentiation factor 15 (GDF15)
breast cancer (BC)
secretome
Online Access:https://www.mdpi.com/2072-6694/14/10/2562

Internet

https://www.mdpi.com/2072-6694/14/10/2562

Similar Items