Opioid-induced hyperalgesia: Are thalamic T-type calcium channels treatment targets?
Opioid-induced hyperalgesia (OIH) is a state of paradoxically enhanced pain transmission, termed nociceptive sensitization, described to occur in both humans and animals after repeated administration of opioid drugs, including rapidly acting remifentanil. However, molecular mechanisms of OIH remain...
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| Format: | Article |
| Language: | English |
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American Society for Clinical Investigation
2022-12-01
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| Series: | The Journal of Clinical Investigation |
| Online Access: | https://doi.org/10.1172/JCI165977 |