Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort.

Oxidative stress is believed to be a major driver of inflammation in smoking asthmatics. The U-BIOPRED project recruited a cohort of Severe Asthma smokers/ex-smokers (SAs/ex) and non-smokers (SAn) with extensive clinical and biomarker information enabling characterization of these subjects. We inves...

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Main Authors: Rosalia Emma, Aruna T Bansal, Johan Kolmert, Craig E Wheelock, Swen-Erik Dahlen, Matthew J Loza, Bertrand De Meulder, Diane Lefaudeux, Charles Auffray, Barbro Dahlen, Per S Bakke, Pascal Chanez, Stephen J Fowler, Ildiko Horvath, Paolo Montuschi, Norbert Krug, Marek Sanak, Thomas Sandstrom, Dominick E Shaw, Louise J Fleming, Ratko Djukanovic, Peter H Howarth, Florian Singer, Ana R Sousa, Peter J Sterk, Julie Corfield, Ioannis Pandis, Kian F Chung, Ian M Adcock, René Lutter, Lorena Fabbella, Massimo Caruso, U-BIOPRED Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6150501?pdf=render