Targeting HER2-low in metastatic breast cancer: an evolving treatment paradigm

The results of the Phase III DESTINY-Breast04 trial of trastuzumab deruxtecan (T-DXd) are leading to a shift in both the classification and treatment of human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer. In this trial, T-DXd was associated with a substantial survival...

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Bibliographic Details
Main Authors: Charlie Yang, Christine Brezden-Masley, Anil Abraham Joy, Sandeep Sehdev, Shanu Modi, Christine Simmons, Jan-Willem Henning
Format: Article
Language:English
Published: SAGE Publishing 2023-06-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/17588359231175440