Anticonvulsant effects of cenobamate in chemically and electrically induced seizure models in rodents

Background: Cenobamate is an antiseizure medication used to treat partial-onset (focal) seizures. It is a molecule with one chiral center and a unique dual mechanism of action: enhancement of fast and slow inactivation of sodium channels with preferential inhibition of the persistent current and pos...

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Bibliographic Details
Main Authors: Susan M. Melnick, Yujin Shin, Kelli J. Glenn
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023061285