The Role of CCL24 in Primary Sclerosing Cholangitis: Bridging Patient Serum Proteomics to Preclinical Data

The Role of CCL24 in Primary Sclerosing Cholangitis: Bridging Patient Serum Proteomics to Preclinical Data

Primary sclerosing cholangitis (PSC) is an inflammatory and fibrotic biliary disease lacking approved treatment. We studied CCL24, a chemokine shown to be overexpressed in damaged bile ducts, and its involvement in key disease-related mechanisms. Serum proteomics of PSC patients and healthy controls...

Full description

Bibliographic Details
Main Authors: Raanan Greenman, Tom Snir, Avi Katav, Revital Aricha, Inbal Mishalian, Ophir Hay, Matthew Frankel, John Lawler, Francesca Saffioti, Massimo Pinzani, Douglas Thorburn, Amnon Peled, Adi Mor, Ilan Vaknin
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cells
Subjects:
cholangitis
inflammation
fibrosis
CCL24
chemokines
proteomics
Online Access:https://www.mdpi.com/2073-4409/13/3/209

Internet

https://www.mdpi.com/2073-4409/13/3/209

Similar Items