Importance of immune response genes in hemophilia A

Importance of immune response genes in hemophilia A

Hemophilia A is a disease caused by a deficiency of coagulation factor VIII resulting from genetic inheritance linked to chromosome X. One treatment option is the administration of plasma or recombinant FVIII. However, some patients develop inhibitors or antibodies against this factor. Inhibitors ar...

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Bibliographic Details
Main Authors: Josiane Bazzo de Alencar, Luciana Conci Macedo, Morgana Ferreira de Barros, Camila Rodrigues, Renata Campos Cadide, Ana Maria Sell, Jeane Eliete Laguila Visentainer
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Revista Brasileira de Hematologia e Hemoterapia
Subjects:
Hemophilia A
Blood coagulation
Factor VIII
Major histocompatibility complex
Cytokines
Human Leukocyte Antigen
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842013000400280&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842013000400280&lng=en&tlng=en

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