Reproducibility and Robustness of a Liver Microphysiological System PhysioMimix LC12 under Varying Culture Conditions and Cell Type Combinations

Reproducibility and Robustness of a Liver Microphysiological System PhysioMimix LC12 under Varying Culture Conditions and Cell Type Combinations

The liver is one of the key organs for exogenous and endogenous metabolism and is often a target for drug- and chemical-driven toxicity. A wide range of experimental approaches has been established to model and characterize the mechanisms of drug- and chemical-induced hepatotoxicity. A number of mic...

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Bibliographic Details
Main Authors: Alicia Y. Lim, Yuki Kato, Courtney Sakolish, Alan Valdiviezo, Gang Han, Piyush Bajaj, Jason Stanko, Stephen S. Ferguson, Remi Villenave, Philip Hewitt, Rhiannon N. Hardwick, Ivan Rusyn
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Bioengineering
Subjects:
microphysiological systems
liver
testing
tissue chip
Online Access:https://www.mdpi.com/2306-5354/10/10/1195

Internet

https://www.mdpi.com/2306-5354/10/10/1195

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