The frequency of atrial fibrillatory waves is modulated by the spatiotemporal pattern of acetylcholine release: a 3D computational study

In atrial fibrillation (AF), the ECG P-wave, which represents atrial depolarization, is replaced with chaotic and irregular fibrillation waves (f waves). The f-wave frequency, Ff, shows significant variations over time. Cardiorespiratory interactions regulated by the autonomic nervous system have be...

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Bibliographic Details
Main Authors: Chiara Celotto, Carlos Sánchez, Mostafa Abdollahpur, Frida Sandberg, Jose F. Rodriguez Mstas, Pablo Laguna, Esther Pueyo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1189464/full