Nanomicellar Formulations Loaded with Histamine and Paclitaxel as a New Strategy to Improve Chemotherapy for Breast Cancer

Nanomicellar Formulations Loaded with Histamine and Paclitaxel as a New Strategy to Improve Chemotherapy for Breast Cancer

Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype. Currently, paclitaxel (PTX) represents the first-line therapy for TNBC; however it presents a hydrophobic behavior and produces severe adverse effects. The aim of this work is to improve the therapeutic index of PTX t...

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Bibliographic Details
Main Authors: Melisa B. Nicoud, Ignacio A. Ospital, Mónica A. Táquez Delgado, Jennifer Riedel, Pedro Fuentes, Ezequiel Bernabeu, Mara R. Rubinstein, Paolo Lauretta, Rocío Martínez Vivot, María de los Ángeles Aguilar, María J. Salgueiro, Daniela Speisky, Marcela A. Moretton, Diego A. Chiappetta, Vanina A. Medina
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
nanomicellar formulation
drug delivery
histamine
triple negative breast cancer
paclitaxel
apoptosis
Online Access:https://www.mdpi.com/1422-0067/24/4/3546

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https://www.mdpi.com/1422-0067/24/4/3546

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