Elevated circulating adiponectin levels do not prevent anxiety-like behavior in a PCOS-like mouse model

Abstract Polycystic ovary syndrome (PCOS) is associated with symptoms of moderate to severe anxiety and depression. Hyperandrogenism is a key feature together with lower levels of the adipocyte hormone adiponectin. Androgen exposure leads to anxiety-like behavior in female offspring while adiponecti...

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Bibliographic Details
Main Authors: Manisha Samad, Joakim Ek, Stina Börchers, Jean-Philippe Krieger, Elisabet Stener-Victorin, Karolina P. Skibicka, Ingrid Wernstedt Asterholm, Anna Benrick
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50503-8