Host genetics highlights IFN-γ-dependent Toxoplasma genes encoding secreted and non-secreted virulence factors in in vivo CRISPR screens

Summary: Secreted virulence factors of Toxoplasma to survive in immune-competent hosts have been extensively explored by classical genetics and in vivo CRISPR screen methods, whereas their requirements in immune-deficient hosts are incompletely understood. Those of non-secreted virulence factors are...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Yuta Tachibana, Emi Hashizaki, Miwa Sasai, Masahiro Yamamoto
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Elsevier 2023-06-01
Σειρά:Cell Reports
Θέματα:
Διαθέσιμο Online:http://www.sciencedirect.com/science/article/pii/S2211124723006034