Nanomolar concentrations of the photodynamic compound TLD-1433 effectively inactivate numerous human pathogenic viruses

Nanomolar concentrations of the photodynamic compound TLD-1433 effectively inactivate numerous human pathogenic viruses

The anti-viral properties of a small (≈1 kDa), novel Ru(II) photo dynamic compound (PDC), referred to as TLD-1433 (Ruvidar™), are presented. TLD-1433 had previously been demonstrated to exert strong anti-bacterial and anti-cancer properties. We evaluated the capacity of TLD-1433 to inactivate severa...

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Bibliographic Details
Main Authors: Kevin M. Coombs, Kathleen K.M. Glover, Raquel Russell, Pavel Kaspler, Mark Roufaiel, Drayson Graves, Peter Pelka, Darwyn Kobasa, Roger DuMoulin-White, Arkady Mandel
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Heliyon
Subjects:
Antivirals
Lipid envelope
Photodynamic therapy
TLD-1433
Ruvidar™
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024081714

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024081714

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