Revisiting the slow force response: The role of the PKG signaling pathway in the normal and the ischemic heart

Introduction: The myocardial response to acute stretch consists of a two-phase increase in contractility: an acute increase by the Frank-Starling mechanism and a gradual and time-dependent increase in force generated known as the slow force response (SFR). The SFR is actively modulated by different...

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Main Authors: Ricardo Castro-Ferreira, João Sérgio Neves, Ricardo Ladeiras-Lopes, André M. Leite-Moreira, Manuel Neiva-Sousa, João Almeida-Coelho, João Ferreira-Martins, Adelino F. Leite-Moreira
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Revista Portuguesa de Cardiologia
Online Access:http://www.sciencedirect.com/science/article/pii/S0870255114001796