A comparison of short-read, HiFi long-read, and hybrid strategies for genome-resolved metagenomics

A comparison of short-read, HiFi long-read, and hybrid strategies for genome-resolved metagenomics

ABSTRACTShotgun metagenomics enables the reconstruction of complex microbial communities at a high level of detail. Such an approach can be conducted using both short-read and long-read sequencing data, as well as a combination of both. To assess the pros and cons of these different approaches, we u...

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Bibliographic Details
Main Authors: Raphael Eisenhofer, Joseph Nesme, Luisa Santos-Bay, Adam Koziol, Søren Johannes Sørensen, Antton Alberdi, Ostaizka Aizpurua
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:Microbiology Spectrum
Subjects:
microbiology
metagenomics
long read
mice
gut microbiome
microbiome
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03590-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03590-23

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