Origin of acetylcholine antagonism in ELIC, a bacterial pentameric ligand-gated ion channel

Origin of acetylcholine antagonism in ELIC, a bacterial pentameric ligand-gated ion channel

A structural and functional study of the prokaryotic ligand-gated ion channel, ELIC, provides insight into the origin of agonism and antagonism at nicotinic acetylcholine receptors.

Bibliographic Details
Main Authors: Mykhaylo Slobodyanyuk, Jesús A. Banda-Vázquez, Mackenzie J. Thompson, Rebecca A. Dean, John E. Baenziger, Roberto A. Chica, Corrie J. B. daCosta
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-04227-6

Internet

https://doi.org/10.1038/s42003-022-04227-6

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