NLRX1 Prevents M2 Macrophage Polarization and Excessive Renal Fibrosis in Chronic Obstructive Nephropathy

NLRX1 Prevents M2 Macrophage Polarization and Excessive Renal Fibrosis in Chronic Obstructive Nephropathy

Background: Chronic kidney disease often leads to kidney dysfunction due to renal fibrosis, regardless of the initial cause of kidney damage. Macrophages are crucial players in the progression of renal fibrosis as they stimulate inflammation, activate fibroblasts, and contribute to extracellular mat...

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Bibliographic Details
Main Authors: Ye Liu, Lotte Kors, Loes M. Butter, Geurt Stokman, Nike Claessen, Coert J. Zuurbier, Stephen E. Girardin, Jaklien C. Leemans, Sandrine Florquin, Alessandra Tammaro
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
NLRX1
macrophage polarization
OXPHOS
renal fibrosis
Online Access:https://www.mdpi.com/2073-4409/13/1/23

Internet

https://www.mdpi.com/2073-4409/13/1/23

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