In vitro megakaryocyte culture from human bone marrow aspirates as a research and diagnostic tool

Megakaryocytes (MKs) are relatively rare in bone marrow, comprising <0.05% of the nucleated cells, which makes direct isolation from human bone marrow impractical. As such, in vitro expansion of primary MKs from patient samples offers exciting fundamental and clinical opportunities. As most of th...

Full description

Bibliographic Details
Main Authors: Kirill R Butov, Elena Y Osipova, Nikita B Mikhalkin, Natalia M Trubina, Mikhail A Panteleev, Kellie R Machlus
Format: Article
Language:English
Published: Taylor & Francis Group 2021-10-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2020.1817359