Hypoxia-Inducible Factor-1α (HIF-1α) as a Biomarker for Changes in Microcirculation in Individuals with Systemic Sclerosis

Hypoxia-Inducible Factor-1α (HIF-1α) as a Biomarker for Changes in Microcirculation in Individuals with Systemic Sclerosis

Abstract Introduction Systemic sclerosis is an autoimmune disease characterized by tissue fibrosis and microangiopathy. Vascular changes such as a decrease in capillary density diminish blood flow and impair tissue oxygenation. Reliable ways to monitor disease activity and predict disease progressio...

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Bibliographic Details
Main Authors: Magdalena Maciejewska, Mariusz Sikora, Albert Stec, Michał Zaremba, Cezary Maciejewski, Katarzyna Pawlik, Lidia Rudnicka
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-06-01
Series:Dermatology and Therapy
Subjects:
Biomarker
Digital ulcers
HIF-1α
Hypoxia-inducible factor-1α
Microangiopathy
Systemic sclerosis
Online Access:https://doi.org/10.1007/s13555-023-00952-w

Internet

https://doi.org/10.1007/s13555-023-00952-w

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